Flow Rate Control

Flow rate control is the regulation of how quickly a fluid moves through a biological system, a process essential for delivering nutrients, removing waste, and maintaining stable conditions. It operates by adjusting driving pressure and resistance, often through changes in vessel diameter, valve position, pump activity, or channel geometry. In living organisms, neural and chemical feedback can alter vascular resistance to match tissue demands, while laboratory systems use pumps, regulators, and sensors to maintain defined flow rates. These principles support studies of circulation, perfusion, cell culture, microfluidics, and tissue engineering, where controlled flow influences transport, cell behavior, and experimental reproducibility.

Flow Rate Control - Related Videos

Education

JoVE Science Education - Engineering

Mass Conservation and Flow Rate Measurements

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2023

Source: Ricardo Mejia-Alvarez and Hussam Hikmat Jabbar, Department of Mechanical Engineering, Michigan State University, East Lansing, MI The purpose of this experiment is to demonstrate the calibration of a flow passage as a flowmeter using a control volume (CV) formulation [1, 2]. The CV analysis focuses on the macroscopic effect of flow on engineering systems, rather than the detailed description that could be achieved with a detailed differential analysis. These two techniques should be...

Control of Power Flow

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2024

There are several methods to control power flow in power systems: Prime mover and excitation control of generators Switching of shunt capacitor banks, shunt reactors, and static var systems Control of tap-changing and regulating transformers A simple generator in the system is represented by its Thevenin equivalent circuit, which represents its model operating under balanced steady-state conditions. The key parameters include the generator terminal voltage Vt, the excitation voltage Eg,...

Research

JoVE Journal - Medicine

Quality-Controlled Sputum Analysis by Flow Cytometry

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Cited by 4 •

2021

This protocol describes an efficient method for dissociating sputum into a single cell suspension and the subsequent characterization of cellular subsets on standard flow cytometric platforms.

Parameterizing V-notch Weir Equations for Flow Monitoring in a Drainage Control Structure

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2025

This protocol describes methods for obtaining weir flow equation coefficients for a V-notch weir within a drainage control structure using (1) a laboratory calibration procedure and (2) an online tool, the "Weir Flow Equation Coefficients Calculator", developed by the authors. These methods apply to flows contained within the V-notch and overtopping flows.

Porphyrin-Modified Beads for Use as Compensation Controls in Flow Cytometry

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2023

The protocol describes how porphyrin-based compensation beads for flow cytometry are prepared by the reaction of amine-functionalized polystyrene beads with the porphyrin TCPP and the amide coupling reagent EDC. A filtration procedure is used to reduce the particulate byproducts.

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