Modular Organization

Modular organization is the arrangement of a complex system into semi-independent units, or modules, that perform specialized functions while interacting with one another. In neuroscience, modules can be defined by anatomical structure, patterns of neural connectivity, or shared responses to particular stimuli; specialized processing within each module is coordinated through communication across networks. This organization allows the nervous system to divide complex tasks, integrate information, and adapt activity without requiring every neuron to participate equally in every process. Studying modular organization helps researchers interpret brain function, compare healthy and altered neural networks, and investigate how changes in connectivity contribute to neurological and psychiatric conditions.

Modular Organization - Related Videos

Research

JoVE Journal - Bioengineering

Standardized Modular Assembly of Polycistronic Operons with Modular Cloning (MoClo) using the In-Cloning toolkit

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2025

This article presents a step-by-step protocol demonstrating how Modular Cloning (MoClo) can be adapted for the cloning of polycistronic operons.

Robotics in Surgery: A Modular Robotic Platform Driven Gastric Wedge Resection

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2025

Robotically assisted surgery has become highly popular in recent years. Presented here is the standard care for upper gastrointestinal procedures, including a demonstration of a robotic-assisted gastric wedge resection using a modular robotic device.

Construction of Modular Hydrogel Sheets for Micropatterned Macro-scaled 3D Cellular Architecture

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Cited by 4 •

2016

We describe the fabrication of micropatterned hydrogel sheets using a simple process, which can be assembled and manipulated in a freestanding form. Using these modular hydrogel sheets, a simple macro-scaled 3D cell culture system can be generated with a controlled cellular microenvironment.

Research

JoVE Journal - Genetics

CRISPR-Based Modular Assembly for High-Throughput Construction of a UAS-cDNA/ORF Plasmid Library

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Cited by 1 •

2024

We present a protocol for CRISPR-based modular assembly (CRISPRmass), a method for high-throughput construction of UAS-cDNA/ORF plasmid library in Drosophila using publicly available cDNA/ORF resources. CRISPRmass can be applied to editing various plasmid libraries.

The Zebrafish Tol2 System: A Modular and Flexible Gateway-Based Transgenesis Approach

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Cited by 5 •

2022

This work describes a protocol for the modular Tol2 transgenesis system, a gateway-based cloning method to create and inject transgenic constructs into zebrafish embryos.

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