<p class="jove_content">Here, we present a protocol for the structure-guided design of protein-ligand binding interaction between Sanglifehrin A and Cyclophilin A/Ganoderiol-F, essential in discovering new drugs. The stability of the ligand-receptor complex was evaluated using molecular dynamics simulation.</p>

structure-guided-design-development-novel-cyclophilin-inhibitors

Structure-Guided Design and Development of Novel Cyclophilin A Inhibitors and Ganoderiol-F Derivatives: An <em>In-Silico</em> Approach

The cyclin Ds-CDKs axis (Cyclophilin A (Cyp /Ganoderiol F)) plays a critical role in cancer through various processes, such as controlling proliferation ...

Institution - BBR Pty Ltd

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